Focal Segmental Glomerulous Sclerosis

Focal Segmental Glomerulous Sclerosis Basic

Focal Segmental Glomerulosclerosis (FSGS) refers to a disorder in which scar tissue develops on the kidneys' filters called glomeruli. Untreated, the disease usually leads to Kidney Failure where the only treatment options are dialysis or a kidney transplant.


Glomerulosclerosis is not caused by a single disease. It has several different causes. This scarring may occur due to an infection, or drug toxicity, or a disease that affects the entire body, such as Diabetes, HIV infection, sickle cell disease or lupus. At times, there may be a genetic component in some patients.


A kidney biopsy can be down to make an accurate diagnosis of glomerulosclerosis. In a biopsy, the doctor will remove a very small amount of renal tissue. The tissue is examined for signs of scarring. Diagnosing FSGS may require multiple biopsies, as the scarring does not occur throughout the kidney. The doctor have to look at samples from several different parts of the kidney until an affected area is found. Other tests that may be ordered include GFR, kidney ultrasound, and genetic testing.


Untreated, most patients with FSGS will finally enter into complete kidney failure and require dialysis or a transplant to survive. Even with treatment, many patients will still eventually require dialysis (in around 2-20 years).

Kidney transplant in FSGS

In about 20-50% cases, the disease may return in the transplanted kidney. Risks that may include the recurrence of the disease may include: - Age (< 15 years old); - If the disease took less than 3 years from the diagnosis of the disease to reach kidney failure; - Caucasian race; - Loss of a previous transplant due to return of FSGS. The recurrence of the disease in transplanted kidney occurs very soon after the operation. It can return within hours to days. Most cases will be within the first year after transplantation. More than 50% of people with recurrence of the disease will lost their kidney within 5 years. Of all the patients with this disorder who get a transplant, around 15% will lose the kidney due to recurrent FSGS.

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FSGS Symptoms

People with FSGS usually do not show signs or symptoms of the disease until the progressive kidney damage seriously interfere with the kidney function. If this happens, patients may present symptoms as below:

* Edema, or swelling

The most commonly seen symptoms is edema, or swelling, particularly in the legs. Usually, patients will detect that their shoes no longer fit, or that they have suddenly put on weight. Due to fluid retention of the body, patients may experience swollen feet, ankles, hands, face, or abdomen.

* Protein in urine  

Urine normally contains only a very small amount of protein, as it is too big to pass through the kidneys' filters (glomeruli). However, when the filters become damaged or scarred, they fail to retain protein and will leak protein into the urine. With massive loss of protein, patients will find that their urine looks foamy or frothy.

* Hypertension, or high blood pressure

* Tiredness, or fatigue

Kidney disease patients often experience this symptoms due to anemia, a shortage of oxygen-carrying red blood cells.

* Nausea and vomiting

When kidney damage become worse and worse, excess nitrogen will accumulate in the blood and stimulate the gastrointestinal tract, causing nausea and vomiting. Moreover, other symptoms of FSGS may also include loss of appetite, weight gain, back or flank pain, low blood protein level, elevated blood cholesterol level, fever and chill, etc. To learn more about FSGS symptoms or management, please feel free to Contact Us.

If you have been diagnosed with Kidney Failure, we're here to help. Call us: +86-311-86954186 OR email us: through Sunday) to make an appointment.

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FSGS Treatment

Huaxia Kidney Disease Hospital is a professional Kidney Disease hospital. It will make personalized cure method for each FSGS patients according to their different conditions. There are lots of experts here to provide you the most suitable therapy which is a natural therapy and has no side effect on you.. They can help you to get rid of dialysis or kidney transplant, what's more they can prevent the process of renal fibrosis and repair your damaged kidney functions. Do you want to know it now ? Let us learn it together.

Blood pollution Therapy

As the latest treatment for FSGS, Blood Pollution Therapy is a systematic therapy which not only can alleviate the symptoms but also cure renal disease from the underlying cause. The whole treatment can be divided into three steps, which are remove blood stasis, supplement necessary elements to the blood, and restore the overall renal function.

Micro-Chinese Medicine Osmotherapy

Micro-Chinese Medicine Osmotherapy is a perfect combination of traditional Chinese Medicine and modern high technology. As an external application, it is different from the traditional oral medications, so you need to use it according to your doctors construction. Functions of this remedy may including expand the blood vessels, prevent excess inflammatory response, anti-coagulation, degrade and eliminate harmful substances like immune complex deposits.

TCM Remedies

Available TCM therapies for FSGS kidney disease including Full Bath Therapy, Foot Bath, Acupuncture, Moxibustion, Cycle Therapy, Enema, Qi gong, Tai Chi, etc. All of these therapies can relieve symptoms of your disease, you can consult further informations on our website.

If you have been diagnosed with Kidney Failure, we're here to help. Call us: +86-311-86954186 OR email us: through Sunday) to make an appointment.

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When you have Focal Segmental Glomerulosclerosis (FSGS), your kidneys are no longer working as well as they need to. Changing your dietary arrangement can help protect your kidneys as well as help control symptoms and complications.

1.Most individuals who have been diagnosed with FSGS need to restrict sodium, fluids, and protein. If patients have developed into kidney failure, low-potassium and low-phosphorus diets are also necessary. Consult your dietitian for the most suitable amount of these nutrients in your specific case. Or, Contact Us to get free and professional advice from our kidney experts.

2.there is no diet which can suitable for every FSGS patients.the doctor or dietitian will make a diet plan for you according to your disease.

3.It could be difficult to change your daily dietary arrangement. You may have to give up many foods you like. However, it is quite essential to make the recommended adjustments so you can stay healthy for as long as possible.

4.Your diet may change over time as FSGS develops. See you doctor for regular testing, and work with a dietitian to adjust your diet as needed.

TNutrition is very important in maintaining health and wellbeing, particularly when diagnosed with FSGS. Being careful about what is eaten can reduce the amount of fluid and wastes build-up, helping to minimise symptoms and side effects of kidney disease. Following your suggested nutritional care plan may not treat or cure your kidney problem, but it could help you improve your general feeling of wellbeing. If you still have anything unclear about managing your renal disease, please feel free to chat with our online service for free and professional help. It's our pleasure to share useful information!

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FSGS Healthy Living

Kidney Disease can develop into Kidney Failure over time, but if you can find it earlier, lifestyle changes can preserve the remaining functions of your kidneys and relieve the symptoms or discomforts. The following sections give lifestyle tips and specific advices for people with kidney disease on how to keep well. A healthier lifestyle can helps to reduce the risk of illness.

•Limit the intake of salt, protein, cholesterol, and sugar in the diet. Consult your dietitian for the most suitable meal plan.

• Keep your blood pressure under control. If you have Diabetes, be strict on your blood sugar levels, that will be helpful for your health.

• Do not smoke and keep away from alcohol .

• Exercise regularly and avoid stress.

• Take medicines according to your doctor's construction. Before buying any medicines over the counter, please tell the pharmacist about your kidney problems and the medicines you are prescribed.

• If you are on peritoneal dialysis or hemodialysis treatment using a line, follow the advices given to you about the care of your line or peritoneal dialysis catheter and report any problems promptly. If you feel uncomfortable or need advices, please contact your kidney doctor as early as possible.

• Have faith in yourself. Having FSGS is a challenge, but believing in yourself can help you to prevail. You can do this!

• Proper work is good for you. If you have job, or if you spend your time volunteering, realize that having an outlet that enables you to feel competent and productive is positive for your total well-being. Continuing your work schedule help you stay connected and improve your quality of life.

Hope the above informations can be helpful for you to live a healthy life with FSGS. If you still have other questions, please feel free to let us know.

If you have been diagnosed with Kidney Failure, we're here to help. Call us: +86-311-86954186 OR Email us: through Sunday) to make an appointment.

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